Description of Topical Anti-allergic Agents
Antihistamines : Histamine, a chemical agent causes allergic reactions. Anti-histamine agents are used so as to counteract the actions of histamine.
Topical Topical Anti-allergic Agents/ Anti-histaminic Agents
- Pheneramine Maleate
- Levocobastine hydrochloride
- Emedastine difumarate ophthalmic solution
- Antazoline ophthalmic solution
- Azelastine hydro-chloride
Pheneramine Maleate
A histaminic agent used extensively in mild to moderate ocular allergic disorders.
Most of the time it is used along with Phenylephrine and or Naphazoline Eye drops.
2) Levocabastine Hydrochloride
A potent antihistaminic agent. It provides relief within few minutes.
Dosage > Ophthalmic suspension 0.05 per cent I drop 4 times/daily dose.
3) Emedastine Difumarate
Selective HI receptor antagonist.
Indication > Allergic conjunctivitis
Dosage > Ophthalmic solution 0.05 per cent 1 drop 4 times/day.
Adverse Reaction > Burning sensation, headache, blurred vision
4) ‘Azetastine Hydrochloride
It is an antihistaminic agent. It also has leukotriene and platelet aggregating factor antagonistic activity.
Indications
i) Seasonal allergic conjunctivitis
ii) Vemal kerato conjunctivitis
Dosage > Ophthalmic solution 0.05 per cent, 3 drop 3 to 4 times/day.
Adverse Reaction > Burning sensation, local imitation
