Description of Topical Anti-allergic Agents
Antihistamines : Histamine, a chemical agent causes allergic reactions. Anti-histamine agents are used so as to counteract the actions of histamine.
Topical Topical Anti-allergic Agents/ Anti-histaminic Agents
- Pheneramine Maleate
- Levocobastine hydrochloride
- Emedastine difumarate ophthalmic solution
- Antazoline ophthalmic solution
- Azelastine hydro-chloride
Pheneramine Maleate
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A histaminic agent used extensively in mild to moderate ocular allergic disorders.
Most of the time it is used along with Phenylephrine and or Naphazoline Eye drops.
2) Levocabastine Hydrochloride
A potent antihistaminic agent. It provides relief within few minutes.
Dosage > Ophthalmic suspension 0.05 per cent I drop 4 times/daily dose.
3) Emedastine Difumarate
Selective HI receptor antagonist.
Indication > Allergic conjunctivitis
Dosage > Ophthalmic solution 0.05 per cent 1 drop 4 times/day.
Adverse Reaction > Burning sensation, headache, blurred vision
4) ‘Azetastine Hydrochloride
It is an antihistaminic agent. It also has leukotriene and platelet aggregating factor antagonistic activity.
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Indications
i) Seasonal allergic conjunctivitis
ii) Vemal kerato conjunctivitis
Dosage > Ophthalmic solution 0.05 per cent, 3 drop 3 to 4 times/day.
Adverse Reaction > Burning sensation, local imitation
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